hrp0082np1.2 | Micro-RNAs in Health and Diseases | ESPE2014

The Role of MicroRNAs in Diabetes

Regazzi Romano

Background: MicroRNAs are small non-coding RNAs that regulate gene expression and play major roles in many physiological and pathological processes.Objective and hypotheses: Determine whether changes in microRNA expression contribute to β-cell dysfunction and/or loss and favor the development of diabetes.Method: Analysis of the changes in microRNA expression occurring in pancreatic islets of diabetes animal models and assessme...